IBS, Inflammation, and Immune Homeostasis, Immune BalancePosted on Tuesday, November, 15th, 2011 by in Chronic Disease | Immune Homeostasis (Immune Balance) | Inflammation
A recent guest post on kevinmd.com by Sophie Lee expressed her frustration and anger at physicians who dismiss her reports of pain with her severe bouts of irritable bowel syndrome (IBS). She repeatedly hears, “it isn’t really serious” “you will just have to live with it, etc. [ www.ibstales.com ].
I just do not get why conventional “wisdom” is that IBS is not an inflammatory disorder. Perhaps pain is possible without inflammation, but that would be atypical. My contention is that if the immune system was in homeostasis, autoimmune disease would either not occur, or it would be limited.
For years I have been questioning “experts”, how is it that IBS is categorized as an autoimmune* disease, yet you claim there is no inflammatory response in the gut?
Current research supports my contention. Recent studies are providing evidence that low levels of inflammation, along with immune mast and other immune cells, are found in the small and large intestines. Mast cells are typically associated with allergic reactions such as runny noses, watery eyes, swelling, and excessive mucous. The mast cells in the intestines appear to be involved in immune homeostasis, in helping the immune system balance.
Interestingly, many of the immune cells found in the gut are in close proximity to nerve cells. .. “Cross-talk” between these cells may explain the pain and other symptoms that individuals experience, and support the hypothesis of a brain-gut axis event in IBS.
It is time for individuals that have “tried everything”, to give their bodies a chance to heal naturally. The immune system has caused the problem, and the immune system can be gently guided to down-regulate overly active responses.
The key to greater comfort may be as simple as helping the body return to immune homeostasis. I hold a patent in the area of immune homeostasis and gut health, and numerous anecdotal reports suggest that balancing immune inflammatory responses makes a major difference in the quality of life of such individuals. Additionally there is a published clinical report by Mark Morningstar, DC, Grand Blanc, MI supporting the relationship between immune homeostasis and healthy bowel function.
One has everything to gain by letting one’s own body rebalance and limit inflammatory responses.
*The immune system mistakenly attacks “self”, the body’s own healthy tissues.