Header image

Studies conducted over the years have shown numerous benefits of using aspirin, a compound with potent
anti-inflammatory properties. If aspirin were discovered today, it would probably be available only through prescription, and cost us 10-40 fold more than we pay for it today.

Additionally, in the area of cancer, laboratory studies suggest that certain anti-inflammatory drugs may prevent certain types of cancers. However, human clinical trials on the efficacy of aspirin for reducing the risk of cancer, and its ability to make a difference in the course of cancer, are uncertain.

Dr. Jean Tang and her colleagues at Stanford University School of Medicine, CA. recently published a study examining how daily intake of aspirin effects the risk of getting melanoma, a deadly type of skin cancer. A study of 60,000 Caucasian women [lighter-skinned individuals are at greater risk of getting skin cancer] ran for an average of 12 years and involved women 50 years to 79 years of age.

Women who took aspirin twice weekly had on average, a 21 %reduction in their risk of getting melanoma  compared to those who did not use aspirin regularly. Women who had taken aspirin twice weekly for at least 5 years had a 30% lower chance of getting melanoma. Other pain relievers such as acetaminophen (found in Tylenol) made no difference in melanoma rates.

Dr. Tang said, “There’s a lot of excitement about this because aspirin has already been shown to have protective effects on cardiovascular disease and colorectal cancer in women”… “This is one more piece of the prevention puzzle.” Dr. Tang feels that the ability of aspirin to limit inflammation may contribute to its association in reducing the risk of cancer. In future studies, Dr. Tang is planning to see whether a similar association is holds for men.

Inflammation is necessary for healing and recovery, but run-away inflammation may be the main contributor to disease. Cancer is a two-way street. Inflammation feeds cancer and cancer feeds inflammation. We need enough of an immune response to stop the growth of cancer cells, but not so much that it “feeds” the growth of mutant cells.

Immune homeostasis, immune balance, is the key to excellent health. Control inappropriately high inflammatory responses of the immune system, and change the course of disease both for the present and in the future.

http://www.ncbi.nlm.nih.gov/pubmed/23589729
http://www.ncbi.nlm.nih.gov/pubmed/18577752
http://onlinelibrary.wiley.com/doi/10.1002/cncr.27817/abstract
http://www.medicinenet.com/script/main/art.asp?articlekey=168421
http://med.stanford.edu/ism/2013/march/tang.html
http://consumer.healthday.com/Article.asp?AID=674264
http://jnci.oxfordjournals.org/content/current

 

It is ten years since the horrific 9/11/01 attacks on the World Trade Center in New York City, The Pentagon in Washington, DC, and Flight 93 in Pennsylvania. On that day at the World Trade Center alone, there were approximately 3,000 murders.

These events have not only left the families, friends, and citizen survivors distraught and at great emotional and financial risk, but the heroic responders, the rescuers, recovery, and clean-up personnel, and civilians that lived and worked in the area, continue to pay a significant price in terms of their health.

There will never be a true accounting of how many individuals were exposed to smoke, thick-coatings of dust, combustion materials, asbestos, polychlorinated biphenyls (PCBs), dioxin, asbestos, and metals. Fire fighters, police, military members, paramedics, construction and iron workers, municipal employees, security workers, residents and workers in the area, and those that came from afar to help, were exposed to these toxic chemicals for days, weeks, and months. Fires burned for 69 days and even eight months after the destruction, workers were still searching for body fragments (1).

For some, the years may be receding from memory, but there are many individuals, and rescue and recovery dogs, that have, or are, still, paying a significant price for their heroic sacrifices. If they are still alive, their emotional and physical health has declined significantly, and no one seems to be able to help them.

Only limited funding has been available to study and monitor individuals that were at Ground Zeroand its surrounding environs. When researching information for this article I was surprised at the relatively few, peer-reviewed publications on this topic, and there is even less information on the effects of this trauma on children and adolescents.

Multiple Health Issues

A primary investigation now led by Dr Juan Wisnivesky, Mount Sinai School of Medicine in New York, has said, “Our findings show a substantial burden of persistent physical and mental disorders in rescue and recovery workers who rushed to the site of the WTC and labored there for weeks and months. Many of these individuals now suffer from multiple health problems (2), since World Trade Center-related mental and physical health conditions often co-exist (3).

Mental Health Issues Persist

One year after 9/11, it was estimated that more than 420,000 people New Yorkers were suffering from post traumatic stress disorders (PTSD) as a result of the attacks (1). This month, the prestigious British journal, Lancet, reports that 32% of tested personnel experienced post traumatic stress disorders and 28% per cent experienced depression at some time after 9/11. The incidence of most of the disorders was highest in workers with greatest World Trade Center exposure (3,4). Other emotional problems such as recurring nightmares, flashbacks, self-medication with alcohol, etc. have also been persistent issues.

Tomorrow: 9/11 Responders: Cancer Risks, Pulmonary Function, Immune Homeostasis, Balance.

1) www.guardian.co.uk/world/2002/aug/18/usa.terrorism

2) www.thelancet.com/journals/lancet/article/PIIS0140-6736(11)61180-X/abstract

3) www.guardian.co.uk/world/2011/sep/02/world-trade-centre-rescuers-health-risk

4) www.thelancet.com/journals/lanonc/article/PIIS1470-2045(01)00543-5/fulltext

css.php